Gabapentin and Stage 3 Kidney disease

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My 14 year old dog has been prescribed Gabapentin 200mg every 12hr for his increasing lameness due to ED and associated OA but has Stage 3 kidney disease, what is the likely impact on his kidneys? Should I approach my vet and ask about Galliprant?
Prior to his CKD diagnosis in January 2018 he was on Meloxidyl, Yumove and Arden Grange food however he has had no pain relief or anti-inflammatories until December when I tried Pardale V which doesn’t agree with him. Thank you

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hey there

  1. yes gabapentin does require the kidneys to be functional to excrete it in the urine, so dosing should bare this in mind and be initiated at the lower end and titrated up looking for effect or possible side effects such as drowsiness etc
  2. yes galliprant suggests that it should be safe on the kidneys but it is still a new drug –¬† I would speak to your vet and if they are unsure – as it is a very new drug to the UK – then the drug company should be able to advise
  3. have you tried paracetamol instead or pardale?
  4.  have you used cartrophen?
  5. elbow OA can be very responsive to hydrotherapy, laser, heat therapy, acupuncture, joint mobilisations with a physio, or intra articular therapy such as PRP, stem cells etc – these may be worth discussing with your vet
  6. there is growing evidence for extracorporeal shock wave therapy as well as- ask your vet

I hope that helps


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